{"id":1712,"date":"2016-08-31T11:21:00","date_gmt":"2016-08-31T18:21:00","guid":{"rendered":"https:\/\/info.pediatricsdirectory.com\/?p=1712"},"modified":"2023-08-27T00:24:07","modified_gmt":"2023-08-27T04:24:07","slug":"1712-2","status":"publish","type":"post","link":"https:\/\/pediatricscommunity.com\/info\/1712\/","title":{"rendered":""},"content":{"rendered":"\n<div class=\"iframely-embed\"><div class=\"iframely-responsive\" style=\"padding-bottom: 52.5%; padding-top: 120px;\"><a href=\"https:\/\/www.annualreviews.org\/doi\/abs\/10.1146\/annurev-genom-090314-050024\" data-iframely-url=\"\/\/cdn.iframe.ly\/api\/iframe?url=https%3A%2F%2Fwww.annualreviews.org%2Fdoi%2Fabs%2F10.1146%2Fannurev-genom-090314-050024&#038;key=13076e8bfaec4bc8750fefa8568d8747\"><\/a><\/div><\/div><script async src=\"\/\/cdn.iframe.ly\/embed.js\" charset=\"utf-8\"><\/script>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-3\">\n<div class=\"wp-block-column is-layout-flow\" style=\"flex-basis:33.33%\">\n<figure class=\"wp-block-image size-full\"><a href=\"https:\/\/www.annualreviews.org\/doi\/abs\/10.1146\/annurev-genom-090314-050024\"><img decoding=\"async\" loading=\"lazy\" width=\"229\" height=\"92\" src=\"https:\/\/pediatricscommunity.com\/info\/wp-content\/uploads\/2023\/08\/ANNUAL_REVIEWS.png\" alt=\"\" class=\"wp-image-5633\"\/><\/a><\/figure>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow\" style=\"flex-basis:66.66%\">\n<h4 class=\"wp-block-heading\"><a href=\"https:\/\/www.annualreviews.org\/doi\/abs\/10.1146\/annurev-genom-090314-050024\">Targeted therapies for cystic fibrosis<\/a> <\/h4>\n\n\n\n<p>In recent years, in-depth understanding of genetic and protein structure-function relationships has led to the introduction of <a href=\"https:\/\/www.annualreviews.org\/doi\/abs\/10.1146\/annurev-genom-090314-050024\">targeted therapies<\/a> for patients with specific cystic fibrosis (CF) genotypes. With these advances, CF has become a model of personalized or precision medicine. The near future will see greater access to targeted therapies for most patients carrying common mutations, which will mandate individualized bench-to-bedside methodologies for those with rare genotypes.<\/p>\n<\/div>\n<\/div>\n<span class=\"tags-links\"><a href=\"https:\/\/pediatricscommunity.com\/info\/cystic-fibrosis\/\" rel=\"tag\">cystic fibrosis<\/a><\/span>","protected":false},"excerpt":{"rendered":"<p>Targeted therapies for cystic fibrosis In recent years, in-depth understanding of genetic and protein structure-function relationships has led to the introduction of targeted therapies for patients with specific cystic fibrosis (CF) genotypes. With these advances, CF has become a model of personalized or precision medicine. The near future will see greater access to targeted therapies [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false},"categories":[2230,2229,402],"tags":[850],"_links":{"self":[{"href":"https:\/\/pediatricscommunity.com\/info\/wp-json\/wp\/v2\/posts\/1712"}],"collection":[{"href":"https:\/\/pediatricscommunity.com\/info\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pediatricscommunity.com\/info\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pediatricscommunity.com\/info\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/pediatricscommunity.com\/info\/wp-json\/wp\/v2\/comments?post=1712"}],"version-history":[{"count":2,"href":"https:\/\/pediatricscommunity.com\/info\/wp-json\/wp\/v2\/posts\/1712\/revisions"}],"predecessor-version":[{"id":5635,"href":"https:\/\/pediatricscommunity.com\/info\/wp-json\/wp\/v2\/posts\/1712\/revisions\/5635"}],"wp:attachment":[{"href":"https:\/\/pediatricscommunity.com\/info\/wp-json\/wp\/v2\/media?parent=1712"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pediatricscommunity.com\/info\/wp-json\/wp\/v2\/categories?post=1712"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pediatricscommunity.com\/info\/wp-json\/wp\/v2\/tags?post=1712"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}