{"id":1362,"date":"2022-02-12T18:57:53","date_gmt":"2022-02-12T23:57:53","guid":{"rendered":"https:\/\/info.pediatricsdirectory.com\/?p=1362"},"modified":"2023-09-09T13:21:05","modified_gmt":"2023-09-09T17:21:05","slug":"1362-2","status":"publish","type":"post","link":"https:\/\/pediatricscommunity.com\/info\/1362\/","title":{"rendered":"Car T-cell tx"},"content":{"rendered":"\n<div class=\"wp-block-columns is-layout-flex wp-container-3\">\n<div class=\"wp-block-column is-layout-flow\" style=\"flex-basis:25%\"><i class=\"fas fa-clipboard-check clinicaltrial\"><\/i>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow\" style=\"flex-basis:75%\">\n<h4 class=\"wp-block-heading\">OPEN CLINICAL STUDY: Cognitive Aftereffects of Neurotoxicity in Children  Who Receive (CAR) T-cell Therapy<\/h4>\n\n\n\n<p>There is a critical need to characterize the subacute and long-term neurocognitive outcomes of participants undergoing CAR T-cell therapies. <span class=\"highlighter\">It is unknown how acute toxicity affects attention, learning, memory, processing speed, and higher order cognition<\/span> in participants who are cured of their cancer and survive for many years. Information about subacute and long- term neurocognitive sequelae would help determine whether the acute toxicity of specific CAR T-cell therapies needs to be treated and prevented aggressively or whether it is fully reversible without specific intervention.<\/p>\n\n\n\n<p><strong>MORE INFO:<\/strong> <a href=\"https:\/\/beta.clinicaltrials.gov\/study\/NCT05237986\">ClinicalTrials.gov<\/a><\/p>\n<\/div>\n<\/div>\n<span class=\"tags-links\"><a href=\"https:\/\/pediatricscommunity.com\/info\/car-t-cell-therapy\/\" rel=\"tag\">CAR T-cell therapy<\/a><a href=\"https:\/\/pediatricscommunity.com\/info\/immunotherapy\/\" rel=\"tag\">immunotherapy<\/a><\/span>","protected":false},"excerpt":{"rendered":"<p>OPEN CLINICAL STUDY: Cognitive Aftereffects of Neurotoxicity in Children Who Receive (CAR) T-cell Therapy There is a critical need to characterize the subacute and long-term neurocognitive outcomes of participants undergoing CAR T-cell therapies. It is unknown how acute toxicity affects attention, learning, memory, processing speed, and higher order cognition in participants who are cured of [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false},"categories":[9,372],"tags":[696,1259],"_links":{"self":[{"href":"https:\/\/pediatricscommunity.com\/info\/wp-json\/wp\/v2\/posts\/1362"}],"collection":[{"href":"https:\/\/pediatricscommunity.com\/info\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pediatricscommunity.com\/info\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pediatricscommunity.com\/info\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/pediatricscommunity.com\/info\/wp-json\/wp\/v2\/comments?post=1362"}],"version-history":[{"count":3,"href":"https:\/\/pediatricscommunity.com\/info\/wp-json\/wp\/v2\/posts\/1362\/revisions"}],"predecessor-version":[{"id":5830,"href":"https:\/\/pediatricscommunity.com\/info\/wp-json\/wp\/v2\/posts\/1362\/revisions\/5830"}],"wp:attachment":[{"href":"https:\/\/pediatricscommunity.com\/info\/wp-json\/wp\/v2\/media?parent=1362"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pediatricscommunity.com\/info\/wp-json\/wp\/v2\/categories?post=1362"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pediatricscommunity.com\/info\/wp-json\/wp\/v2\/tags?post=1362"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}