OPEN CLINICAL STUDY: Cognitive Aftereffects of Neurotoxicity in Children Who Receive (CAR) T-cell Therapy

There is a critical need to characterize the subacute and long-term neurocognitive outcomes of participants undergoing CAR T-cell therapies. It is unknown how acute toxicity affects attention, learning, memory, processing speed, and higher order cognition in participants who are cured of their cancer and survive for many years. Information about subacute and long- term neurocognitive sequelae would help determine whether the acute toxicity of specific CAR T-cell therapies needs to be treated and prevented aggressively or whether it is fully reversible without specific intervention.

MORE INFO: ClinicalTrials.gov